• Biophotonics and waves
  • Single Cell / Single Molecule

3BIOT – 3D Biological Optical Tweezers

A

Abstract

The 3BIOT project aims to develop an interactive robotic instrument that allows objects of a few microns in size, such as beads or cells, to be manipulated in three-dimensional space with optical tweezers in culture conditions.

This multi-tweezer system allows the user to exert forces and accurately capture mechanical interactions between cells or objects. It provides an intuitive software environment and a haptic interface recreating topography, texture or feedback force for the user.

Microprinted suspended objects, the “optobots”, are also developed to allow biologists to either :
– manipulate cells while protecting them from prolonged irradiation damage,
– measure the rigidity and elasticity of the cell surface or intracellular force transductions,
– or map the breaking forces between molecules, viruses or cells grafted to the optobot with their receptors on the cell surface.

C

Call

Plate-forme Transcriptome et Epigénome

As a response to the : Call for projets 2019 : Equipment support for the development of innovative technologies to support research in Life Sciences

Call for projets 2019 : Equipment support

Details & Selected Projects
T

Teams

  • Institute for Intelligent Systems and Robotics (ISIR)

    CNRS - French National Centre for Scientific Research
    Sorbonne University

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  • Lymphocyte Cell Biology

    Institut Pasteur

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  • Cell Biology and Cancer

    Curie Institute

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