• Microfluidics
  • Organs-on-chips
  • Single Cell / Single Molecule

Fast prototyping at micron resolution

Industrial partners  Alvéole
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Abstract

Over the last 10 years, microfabrication technologies previously used in the realization of microelectronic chips, MEMS, and sensors (MMS), have found a new purpose in biological research. This is particularly true in the active field of “bio-engineering”, in which standard tools and techniques of MMS have been adapted to the fabrication of microstructured substrates with dimensions and geometries close to those of living systems. Briefly, the photolithography process commonly used in that purpose, is based on the insulation of a photosensitive resist under a UV aligner through a shadow mask (also called photomask) that contains the pattern to be etched. These resolutions can only be obtained by employing a thin layer of chromium patterned on a glass or quartz substrate.

The acquisition of the maskless lithography system thanks to the “DIM ELICIT call for equipment” (μPG 101 from HEILDELBERG instruments) gave us the capability to fabricate microstructured features whose size range from 1 µm to 10 µm (order of magnitude for cells) in surface areas up to 10×10 cm2. This very user-friendly equipment is actually used by ~20 peoples coming from several research teams (ENS, Institut Curie, ESPCI, and ENSCP) to develop theirs projects.

In addition, having an in-house maskless lithography equipment has reduced our dependency time on third parties (from 2 weeks to 2-3 days) and has greatly reduced our costs (~450 euros/mask before).

Hommage à Maxime Dahan

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Call

As a response to the : Call for projects 2017 : Equipment support

Support to shared equipment for the development of innovative technologies for Life Sciences

Details & Selected Projects
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Teams

  • IPGG Technology Platform

    CNRS - French National Centre for Scientific Research
    Pierre Gilles de Gennes Institute
    PSL University

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  • Macromolecules and microsystems in biology and medicine

    Curie Institute

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  • Pole Microfluidics

    CNRS - French National Centre for Scientific Research
    École Normale Supérieure
    Sorbonne University

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  • Biology inspired physics at mesoscales

    Curie Institute

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  • Systems biology of cell polarity and cell division

    Curie Institute

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